H2N2V1, Main, Exploration, bibRecord, 000B12

Potential strategies and biosafety protocols used for dual‐use research on highly pathogenic influenza viruses

Identifieur interne : 000B12 ( Main/Exploration ); précédent : 000B11; suivant : 000B13

Potential strategies and biosafety protocols used for dual‐use research on highly pathogenic influenza viruses

Auteurs : Lanying Du [États-Unis] ; Ye Li [États-Unis, République populaire de Chine] ; Jimin Gao [République populaire de Chine] ; Yusen Zhou [République populaire de Chine] ; Shibo Jiang [États-Unis, République populaire de Chine]

Source :

Reviews in Medical Virology [ 1052-9276 ] ; 2012-11.

RBID : ISTEX:E63C8090DFAB1D2C25ECDD8257369892E0F3ADF8

English descriptors

Teeft :
- Airborne transmissibility, Airborne transmission, Avian, Biosafety, Biosafety labs, Biosafety protocols, Biosecurity, Copyright, Effective vaccines, Fouchier, Fudan university, Gene segments, Hemagglutinin, Historic pandemics, Hong kong, Hpai, Hpai viruses, Human infections, Human populations, Human services, Iavs, Infectious agents, John wiley sons, Laboratory biosafety, Laboratory generation, Mammal, Medical microbiology, Mutant, Nabs, National biosecurity, Outbreak, Pandemic, Pathogenic, Pathogenic virus strains, Pathogenic viruses, Potential strategies, Potential transmission, Protocol, Public health, Reassortant, Respiratory droplet transmission, Transmissibility, Vaccine, Viral, Viral proteins, Virol, Virology, Virus, Virus assembly, Virus replication.

Abstract

Influenza A viruses (IAVs), particularly the highly pathogenic avian influenza H5N1, have posed a substantial threat to public health worldwide. Although the laboratory generation of the mutant influenza virus H5N1 with airborne transmissibility among mammals, which has been considered as a dual‐use research, may benefit the development of effective vaccines and therapeutics against the emerging infectious agents, it may also pose threats to national biosecurity, laboratory biosafety, and/or public health. This review introduces the classification and characterization of IAVs, pinpoints historic pandemics and epidemics caused by IAVs, emphasizes the significance and necessity of biosafety, summarizes currently established biosafety‐related protocols for IAV research, and provides potential strategies to improve biosafety protocols for dual‐use research on the highly pathogenic avian influenza viruses and other emerging infectious agents. Copyright © 2012 John Wiley & Sons, Ltd.

Url:

DOI: 10.1002/rmv.1729

Affiliations:

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<front><div type="abstract">Influenza A viruses (IAVs), particularly the highly pathogenic avian influenza H5N1, have posed a substantial threat to public health worldwide. Although the laboratory generation of the mutant influenza virus H5N1 with airborne transmissibility among mammals, which has been considered as a dual‐use research, may benefit the development of effective vaccines and therapeutics against the emerging infectious agents, it may also pose threats to national biosecurity, laboratory biosafety, and/or public health. This review introduces the classification and characterization of IAVs, pinpoints historic pandemics and epidemics caused by IAVs, emphasizes the significance and necessity of biosafety, summarizes currently established biosafety‐related protocols for IAV research, and provides potential strategies to improve biosafety protocols for dual‐use research on the highly pathogenic avian influenza viruses and other emerging infectious agents. Copyright © 2012 John Wiley & Sons, Ltd.</div>
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Potential strategies and biosafety protocols used for dual‐use research on highly pathogenic influenza viruses

Potential strategies and biosafety protocols used for dual‐use research on highly pathogenic influenza viruses

Source :

English descriptors

Abstract

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Le document en format XML

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